Tezspire Asthma Treatment: Relief That Outlasts Inhalers

Living with severe asthma can feel like a constant uphill battle. Even worse is seeing your child suffer, cycling through inhalers, steroids, and even regular urgent care visits. More than a condition, it can become a daily disruption.
The answer might not be far out of reach. Tezspire (tezepelumab-ekko), a new FDA-approved asthma treatment, is shifting the way allergists approach severe asthma medication. Its lasting impact is the kind of relief that’s making more families and specialists turn to it as a steady option for care.
At Premier Allergy of Texas, we are excited to offer this groundbreaking asthma treatment to patients who have exhausted all options without lasting control. Combined with our personalized care, Tezspire offers a new way forward—fewer flare-ups, more stability, and a long-term approach that finally matches what patients have needed all along.
How Does Tezspire Work?
Tezspire injections help prevent asthma flare-ups by calming the chain reaction that causes them. It works by blocking thymic stromal lymphopoietin (TSLP), a protein in the body that acts like an alarm system.
When TSLP is triggered, it can lead to:
- Inflammation
- Swelling
- Tightness in the lungs
Tezspire steps in early to stop this process before symptoms begin. By targeting inflammation at its source, Tezspire offers more stable asthma control. The result?
- Fewer bad days
- Fewer emergency visits, and
- Improved overall breathing.
As a biological treatment for asthma, Tezspire also works well when combined with simple lifestyle adjustments, such as keeping your home well ventilated or avoiding strong scents at home. Together, these strategies make it easier to manage asthma and prevent unexpected flare-ups.
Who Is Tezspire For?
Tezspire is approved for asthma treatment in adults and children aged 12 and older. Unlike other asthma biologics, the Tezpire patient eligibility is broad. You don’t need to undergo biomarker testing to initiate treatment.
Note: Biomarker testing requires a sample of tissue, blood, or other bodily fluids from the patient. This laboratory test allows doctors to diagnose diseases, determine the most effective treatments, and even predict how they may escalate or calm. With Tezspire, there is no need for this.
How Is It Administered?
Tezpire is given as a single injection once every four weeks. That means no daily pills or multiple inhalers to manage, just one consistent step each month.
It’s designed for people whose asthma is still difficult to control despite regular treatments and medications. If you or your child is still experiencing wheezing, nighttime symptoms, or frequent reliance on a rescue inhaler, it may be time to consider a more powerful option.
Tezspire for Severe Asthma Control
Living with severe asthma often feels like a constant cycle. One moment you're managing symptoms, the next you're dealing with a flare-up or switching medications again. Tezspire was developed to help patients break out of that exhausting pattern and find a steadier rhythm in their everyday lives.
Here’s what the research shows:
- In a 2021 study, Tezspire helped reduce severe asthma attacks by up to 64%
- Patients had fewer flare-ups during high-risk seasons like winter and spring
- Many reported better lung function and easier breathing day-to-day
- Emergency room visits were less frequent
- Some were even able to cut back on their use of oral steroids
For those seeking long-term asthma control, Tezspire offers the opportunity to move forward with greater consistency, fewer disruptions, and the relief of knowing your treatment is working with you, not against you.

What to Expect: Side Effects
Most side effects reported with Tezspire are mild and manageable. But every medication has risks, and Tezspire is no exception. Most Tezspire side effects reported in clinical trials, though mild and manageable, include:
- Sore throat
- Joint or back pain
- Mild redness or swelling where the injection was given
More serious side effects, such as allergic reactions, are rare. If you experience symptoms such as facial swelling, a rash, or trouble breathing, please contact your healthcare provider immediately.
The good news? Overall, Tezspire has maintained a strong safety record. If you’re considering trying this biological treatment for asthma, consult your local allergist. They can walk you through the risks, benefits, and what to expect.
Your Next Step
Still feeling stuck in the cycle of maintenance meds and flare-ups? Tezspire may offer a different path. It isn’t meant to replace your entire treatment plan but to add stability.
Many people are expected to qualify for this treatment, but no two cases of asthma are the same. Consider scheduling an evaluation for asthma treatment at Premier Allergy of Texas to find out if this is the best treatment for you.
Here’s what to expect during your visit:
- Schedule your appointment online or by phone. Check insurance plans may require a referral, so it’s best to check ahead of time.
- Your first consultation typically lasts two to three hours. It includes a comprehensive medical history, a physical examination, and a discussion about your symptoms.
- Diagnostic testing may be recommended, such as breathing tests or allergy screenings, depending on your condition.
- A custom treatment plan will be created based on your results. This may include Tezspire, allergy shots, or other medications.
- If you begin treatment, your allergist will walk you through the next steps and schedule regular follow-ups to track your progress.
- Ongoing support is available for medication access, insurance coordination, and addressing any questions that may arise along the way.
Trust Premier Allergy of Texas for Lasting Asthma Relief
Asthma can feel like a moving target. Just when things seem manageable, symptoms resurface, and you’re back to square one. But what if you could interrupt that pattern before it starts?
Tezspire shifts the focus from chasing relief to building reliable control. For patients who have struggled to find long-term stability, that change can make a significant difference.
At Premier Allergy of Texas, we offer personalized evaluations to determine if Tezspire is the right fit for you. As one of San Antonio’s trusted asthma clinics, we’re proud to offer this next step in care, combining our passion-driven expertise with treatments that target your unique needs.
Managing asthma doesn’t have to feel out of reach anymore.
Take Control before the Next Flare-up.
Frequently Asked Questions
How is Tezspire administered?
Tezspire is a subcutaneous injection administered once every four weeks, given in-clinic by trained staff at Premier Allergy of Texas, with a short observation period following each dose. If your child is also attending school or daycare, pairing treatment with a plan for avoiding back‑to‑school allergy and asthma triggers can help keep symptoms stable between visits.
How long does it take Tezspire to work?
Most patients notice improvements in symptoms and fewer flare-ups within a few weeks. Response times can vary.
Can Tezspire be used with other asthma medications?
Yes. Tezspire is designed to work in conjunction with your existing asthma treatment plan, not replace it.
Are there any long-term risks with using Tezspire?
Tezspire has shown a strong safety profile in clinical studies. Your doctor can monitor for any issues and adjust your treatment if needed.